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多发伤患者血清降钙素原的水平及临床意义

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摘要 【目的】研究多发伤患者血清降钙素原的变化,并探讨其与损伤严重度、感染及多器官功能障碍综合征(MODS)的关系。【方法】检测64例多发伤患者伤后第1,3,5天血清降钙素原水平,同时评定损伤严重度评分(ISS)值,记录血常规、血糖、血清丙氨酸转氨酶(ALT)、肌酐(Cr)、感染和MODS情况。【结果】多发伤患者血清降钙素原水平显著高于正常对照组(P<0.01)。发生MODS组降钙素原,白细胞计数、ISS值、血糖、血清丙氨酸转氨酶(ALT)和肌酐(Cr)均明显高于脏器功能正常组(P<0.05);发生感染前后,降钙素原差异有统计学意义(P<0.01)。【结论】多发伤可引起降钙素原升高,且与损伤严重程度、感染、MODS有关;检测降钙素原变化有助于及早发现感染和预警MODS的发生。
出处 《中山大学学报(医学科学版)》 CAS CSCD 北大核心 2008年第S1期134-135,共2页 Journal of Sun Yat-Sen University:Medical Sciences
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