代谢综合征各组分及其聚集与2型糖尿病的相关性

Relationship between type 2 diabetes and gathered components of metabolic syndrome

目的探讨代谢综合征(Metabolic Syndrome MS)各组分与2型糖尿病(T2DH)的相关性。方法调查分析202例成人MS患者,并与187例同期其他病人作对照,用多因素logistic回归分析方法,分析MS各组分与DM的相关性。结果MS组与对照组组分特点比较,其HOMA-IR(胰岛素抵抗指数)、BMI(体重指数)、WC(腰围)、TG(甘油三脂)、HDL(高密度脂蛋白)、SBP(收缩压)、DBP(舒张压)差异有统计学意义;MS各组分:中心性肥胖、SBP、DBP、TG水平与糖尿病独立相关性,HDL-C不相关。结论代谢综合征各组分与2型糖尿病密切相关,是T2DM发病的重要危险因子。

Objective To explore the relationship between the type 2 diabetes and gathered components of metabolic syndrome. Methods Investigated 202 cases of adult patients with metabolic syndrome, while 187 pa- tients in the same period were used as comparison, analyzed the relation between type 2 diabetes and every component of the metabolic syndrome by logistic regression analysis. Results The differences of HOMA-IR、 BMI (body mass index)、 WC、 TG、 HDL、 SBP、 DBP are of statistic significance, compared the MS compo- nents characteristics of the MS patients and the control group. MS components: central obesity、 SBP、 DBP、 TG levels associated with diabetes independently, while HDL-C is not relevant to diabetes. Conclusion The vari- ous components of metabolic syndrome, which are closely related to type 2 diabetes, can be important risk fac- tors to the incidence of T2DM.