MCV和RDW对骨髓增生异常综合征鉴别诊断价值的研究

Application of MCV and RDW in the differential diagnosis of MDS and IDA

目的:探讨平均红细胞体积(MCV)和红细胞体积分布宽度(RDW)在骨髓增生异常综合征(MDS)和缺铁性贫血(IDA)鉴别诊断中的应用价值和意义。方法:ABX MICROS60自动血液分析仪检测23例MDS患者和31例IDA患者的MCV、RDW值。结果:MDS和IDA患者的MCV分别为(103.1±10.8)fl和(73.7±9.6)fl,差异有统计学意义(P<0.01)。而MDS和IDA患者的RDW分别为(18.7±4.4)和(17.6±2.8)均高于正常参考值,2组间数据比较,差异无统计学意义(P>0.05)。MDS患者MCV、RDW增高,IDA患者MCV减低、RDW增高。结论:MCV、RDW的变化在MDS和IDA鉴别诊断中有较高的应用价值。

Objective:To investigate the value and significance of mean corpuscular volume(MCV) and red cell distribution width(RDW) in the differential diagnosis of patients with myelodysplastic syndrome(MDS) and iron deficiency anemia(IDA).Methods:MCV and RDW of 23 patients with MDS and 31 patients with IDA were detected by ABX MICROS60 automatic blood analyser.Results:The data of MCV of patients with MDS and IDA were(103.1±10.8)fl and(73.7±9.6)fl,respectively.The results showed a significantdifference(P<0.01).The data of RDW of MDS and IDA patients were (18.7±4.4) and(17.6±2.8),respectively,which both were obviously higher than normal reference value.The difference between the results of the two groups has no significance(P>0.05).The data of MCV and RDW of MDS patients were both increased.All the IDA patients showed the lower level of MCV and the higher level of RDW.Conclusions:It may be high value of the changes of MCV and RDW in the differential diagnosis of MDS and IDA.