摘要
目的了解住院患者感染的金黄色葡萄球菌对常用抗菌药的耐药情况,指导临床合理使用抗菌药。方法应用Walk Away96SI微生物自边分析仪对2009—2010年各科室分离的101株金黄色葡萄球菌的药敏结果进行统计分析。结果分离出的101株金黄色葡萄球菌中耐甲氧西林金黄色葡萄球菌(MRSA,占20.8%)对青霉素、头孢唑啉、本唑西林、氨苄西林、阿莫西林/克拉维酸100%耐药,对利奈唑胺、万古霉素、链阳性菌素复方制剂100%敏感。甲氧西林敏感金黄色葡萄球菌(MSSA,占79.2%)对氨苄西林、青霉素耐药率分别为71.3%和75.0%,对利奈唑胺100%敏感。结论金黄色葡萄球菌除对青霉素和氨苄西林表现出高耐药性外,体外抗菌活性均较好,尤其是利奈唑胺耐药率为0,可作为临床用药参考依据。
[Objective]To understand the drug resistance of Staphylococcus aureus isolated from hospital inpatients,so as to guide the rational use of antibiotics. [Methods]The drug sensitivity results of 101 Staphylococcus aureus strains isolated in our hospital from 2009 to 2010 were analyzed statistically by Walk Away96SI. [Results]100% of methicillin-resistant Staphylococcus aureus(MRSA,which accounted for 20.79% of 101 Staphylococcus aureus strains) were resistant to penicillin,cefazolin,oxacillin,ampicillin and amoxicillin/clavulanic acid.100% of MRSA were sensitive to linezolid,vancomycin and streptogramin.The resistance rate of methicillin-sensitive Staphylococcus aureus(MSSA,which accounted for 20.79% of 101 Staphylococcus aureus strains) to ampicillin and penicillin was 71.25% and 75% respectively,and 100% of MSSA were sensitive to linezolid. [Conclusion]Staphylococcus aureus showed high resistance to penicillin and ampicillin,and the drug resistance to other antibiotics was low,especially to linezolid(0).This result can be used as a reference for clinical treatment.
出处
《职业与健康》
CAS
2011年第22期2614-2615,共2页
Occupation and Health
关键词
金黄色葡萄球菌
耐甲氧西林金黄色葡萄球菌
甲氧西林敏感金黄色葡萄球菌
耐药性
Staphylococcus aureus
Methicillin-resistant Staphylococcus aureus(MRSA)
Methicillin-sensitive Staphylococcus aureus(MSSA)
Drug resistance