抗感染性药物用于非感染性疾病治疗的弊端

Restricting Strictly the Application of Antibiotics in Treating Non-infective Disease

目的呼吁严格限制抗微生物药物用于治疗非感染性疾病。方法根据抗微生物药物临床应用的相关报道,分析存在的弊与利、害与益。结果抗微生物药物在治疗非感染性疾病时,其杀菌和抑菌作用即成为治疗中的不良反应,不仅会破坏患者个体体内正常寄生菌群的平衡,引起继发感染;而且其广泛性和长期性的用药特点,将导致耐药性微生物的产生和发展。结论非感染性疾病的治疗有许多其他有效的药物,并非到了不用抗微生物药物不可的地步,因此应该把遏制微生物耐药性、保护现有抗微生物药物资源作为首要任务。

OBJECTIVE To appeal for restricting strictly the application of antibiotics in treating non-infective disease.METHODS According to the related report of the clinical application of antibiotics,its gains and losses were analyzed.RESULTS The While antibiotics was used to treat non-infective disease,its killing and suppressing bacterial action was changed into side effect in medical treatment.The balance of the normal bacterial flora was broken : causing intestinal flora imbalance,super infection or invading and planting certainly the harmful bacterial;but also its extensive and long-term characteristics will cause the production and the development of drug resistant bacterial.CONCLUSION A lot of other effective drugs exist in treating non infection disease.The situation that antibiotics must be used does not exist.So,we should carefully apply antibiotics,protect the anti bacterial medical resources.