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Structural Analysis and Physicochemical Properties of the Collagen Sponge

Structural Analysis and Physicochemical Properties of the Collagen Sponge
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摘要 This paper summed up experimental data for the structural analyses and properties of collagen sponge to be used as wound dressing or scaffolds of cell growth in tissue engineering. The structural analyses included UV spectrum, amino acid and electrophoresis, while the physicochemical properties were bulk density, water-binding capacity, digestibility and residue on ignition. The structural analysis showed that the collagen sponge made from bovine tendon was purely composed of type Ⅰ collagen, and contained many aggregated compositions with high molecular mass owing to the storage under ambient condition. The bulk density of the collagen sponge was between 18 and 21 mg/cm 3, water-binding capacity from 44 to 53 mg/mg, digestive time about half an hour and residue on ignition between 0.42% and 0.45%. This paper summed up experimental data for the structural analyses and properties of collagen sponge to be used as wound dressing or scaffolds of cell growth in tissue engineering. The structural analyses included UV spectrum, amino acid and electrophoresis, while the physicochemical properties were bulk density, water-binding capacity, digestibility and residue on ignition. The structural analysis showed that the collagen sponge made from bovine tendon was purely composed of type Ⅰ collagen, and contained many aggregated compositions with high molecular mass owing to the storage under ambient condition. The bulk density of the collagen sponge was between 18 and 21 mg/cm 3, water-binding capacity from 44 to 53 mg/mg, digestive time about half an hour and residue on ignition between 0.42% and 0.45%.
出处 《Chinese Journal of Biomedical Engineering(English Edition)》 2003年第3期126-132,共7页 中国生物医学工程学报(英文版)
关键词 TypeⅠcollagen PHYSICOCHEMICAL PROPERTIES STRUCTURAL analysis TypeⅠcollagen,Physicochemical properties,Structural analysis
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