原发性高血压病血尿酸浓度与肾损害关系的临床探讨

Cinical Exploration of Relationship between the Concentration of Plasma Uric Acid and Kidney Damage with Essential Hypertension

目的 探讨原发性高血压病患者血尿酸浓度与早期肾损害的关系。方法 测定120例原发性高血压病患者的血尿酸与血肌酐浓度,分高、中、低尿酸组,血尿酸≥410μmol/L,血肌酐≥177μmol/L为增高。结果 本组血尿酸增高者31例,占25.8％,其中22例血肌酐浓度增高,与中低尿酸组比较有显著差异。结论 原发性高血压病患者血尿酸浓度增高常见,与血肌酐增高呈一致性,可作为高血压病紧损害的观察指标之一。

Objective To Explore the relationship of the concentration of plasma uric acid and early kidney damage in patients with essential hypertension. Methods The concentration of serum uric acid and serum creatinine in 120 patients with essential hypertension were measured. The patients were divide into three(high,medium,low)groups. The high group means serum uric acid ≥410μmol/L and serum creatinine ≥177μmol/L. Results 31 cases occurred high levels of serum uric acid. The concentration of serum creatinine were increased in 22 case. There are significantly difference comparde with medium and low group. Conclusion The patients with essential hypertension often occurred high levels of serum uric acid and consistency of the high levels of serum creatinine . It is one of observation parameters for kidney damage caused by essential hypertension.