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Specific degradation of keratin in Xenopus laevis egg extracts undergoing apoptosis 被引量：1

Specific degradation of keratin in Xenopus laevis egg extracts undergoing apoptosis
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摘要 Cytochrome c activates apoptosis specific protease XCPP32 when being added to Xenopus laevis egg extracts, and induces apoptosis in this cell-free system. During apoptosis, cyto-skeleton proteins in egg extracts are degraded. Western blot assay indicates that 42-ku acidic keratin in egg extracts has been degraded by XCPP32. The degradation of 42-ku keratin may be crucial in apoptosis. Cytochrome c activates apoptosis specific protease XCPP32 when being added to Xenopus laevis egg extracts, and induces apoptosis in this cell-free system. During apoptosis, cyto-skeleton proteins in egg extracts are degraded. Western blot assay indicates that 42-ku acidic keratin in egg extracts has been degraded by XCPP32. The degradation of 42-ku keratin may be crucial in apoptosis.
作者 Shan Zhu Zhigang Lu Yingli Sun Zhonghe Zhai
机构地区 Beijing Univ
出处 《Chinese Science Bulletin》 SCIE EI CAS 2000年第21期1977-1981,共5页
关键词 APOPTOSIS KERATIN XENOPUS LAEVIS EGG extracts CYTOCHROME c XCPP32. apoptosis keratin Xenopus laevis egg extracts cytochrome c XCPP32
分类号 R363 [医药卫生—病理学]
  • 相关文献

参考文献14

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共引文献3

同被引文献18

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引证文献1

Chinese Science Bulletin
2000年 第21期

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