氯沙坦治疗充血性心力衰竭的临床观察

The Clinical Use Assessment of Cozaar on Congestive Heart Failure

目的:观察氯沙坦对充血性心力衰竭左心功能的影响。方法:冠心病、高血压病、扩张型心肌病、风湿性心脏病性心力衰竭患者共38例,在强心、利尿治疗的基础上,每天给予氯沙坦50mg口服治疗,疗程12周。作治疗前、后NYHA分级,心功能的对照分析。结果:治疗后NYHA分级、心功能均得到改善。结论:氯沙坦治疗充血性心力衰竭12周后,能抑制充血性心力衰竭的恶化,改善心功能。

Objective: To observe Lhe therapeutic effects on left ventriculr heart function of Cozaar on congestive heart failure(CHF). Methods: 38 patients with congestive heart failure caused by coronary heart disease, primary hypertension, dilated eardiomyopathy and rheumatic valvular heart disease, were treated with Cozaar(50mg, PO, Qd), in combination with positively inotopic agents and diuretics. The treatment will be sustained of three months. We observed the following data: NYHA class, LVEF, △D% , CI, E/A, C/T. Results: This kind of treatment has got reducion in ventricular remodeling and improvement in heart function, not only systolic but also diastolic function. Conclusions: Cozaar is an effective agent in the treatment of CHF.