特比萘芬治疗头癣28例

Terbinafine in treating tinea capitis in 28 patients

目的 :观察特比萘芬治疗头癣的疗效。方法 :选用 2 8例病人 ,男性 19例 ,女性 9例 ,年龄 9a±s 3a ,病程 5mo± 2mo ,其中白癣 12例 ,黑癣 2例 ,脓癣 14例。口服特比萘芬片 ,病人体重 <2 0kg ,6 2 .5mg ,qd ;2 0～ 4 0kg ,12 5mg ,qd ;>4 0kg ,2 50mg ,qd。同时外用特比萘芬软膏涂抹患处 ,bid。6例脓癣病人加服罗红霉素 (病人体重 2 4～ 4 0kg者10 0mg ,bid ;12～ 2 3kg者 50mgbid)及外用莫匹罗星软膏 ,bid。疗程均为 4wk ,2wk复查 1次。结果 :2 8例头癣病人均在 8wk内痊愈 ,未见不良反应。结论 :特比萘芬治疗头癣 ,疗效确切 ,不良反应少。

AIM: To observe the effect of terbinafine on tinea capitis. METHODS: Among the twenty eight patients (M19, F9; age 9 a± s 3 a, course of disease 5 mo±2 mo), there are 12 tinea alba, 14 kerion and 2 tinea nigra. If body weight is <20 kg, take terbinafine tablts, 62.5 mg, qd; 20～40 kg,125 mg,qd; >40 kg, 250 mg, qd. All the patients were treated with terbinafine hydrochloride unguent, bid. Six kerion patients were given roxithromycin (24～40 kg: 100 mg, bid; 12～23 kg: 50 mg bid) and mupirocin ointment for treatment. All patients received 4 wk treatment as a course, and followed up once every two week. RESULTS: Twenty eight patients were all cured within 8 wk. CONCLUSION: Terbinafine is rather effective and safe in the treatment of tinea capitis.