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The origin of a novel kind of reassortant (H1N2) of influenza A virus

The origin of a novel kind of reassortant (H1N2) of influenza A virus
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摘要 Genetic analysis of three H1N2 viruses indicated that only HA genes of H1N2 viruses were similar to that of A/Guangdong/6/91(H1N1) virus (PR8-like strain), while the other seven genes of them were similar to those of H3N2 virus circulating in man in 1995. Therefore, it could be considered that the H1N2 viruses were derived from reassortment between PR8-like strain and H3N2 virus circulating in man in 1995. However, the genomes of H1N2 viruses were very similar to each other. So the H1N2 viruses isolated in 1998 were not derived from new reassortment between PR8-like strain and H3N2 virus circulating in man in 1998, but derived from the evolution of H1N2 virus found in 1995. Genetic analysis of three H1N2 viruses indicated that only HA genes of H1N2 viruses were similar to that of A/Guangdong/6/91(H1N1) virus (PR8-like strain), while the other seven genes of them were similar to those of H3N2 virus circulating in man in 1995. Therefore, it could be considered that the H1N2 viruses were derived from reassortment between PR8-like strain and H3N2 virus circulating in man in 1995. However, the genomes of H1N2 viruses were very similar to each other. So the H1N2 viruses isolated in 1998 were not derived from new reassortment between PR8-like strain and H3N2 virus circulating in man in 1998, but derived from the evolution of H1N2 virus found in 1995.
出处 《Science China(Life Sciences)》 SCIE CAS 2000年第5期519-525,共7页 中国科学(生命科学英文版)
关键词 INFLUENZA A VIRUS a NOVEL KIND of REASSORTANT origin. influenza A virus, a novel kind of reassortant, origin.
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  • 1D. Anchlan,S. Ludwig,P. Nymadawa,J. Mendsaikhan,C. Scholtissek.Previous H1N1 influenza A viruses circulating in the Mongolian population[J].Archives of Virology.1996(8)
  • 2Nakajima,K.Desselberger, U[].Palese R Recent human influenza A (HN) viruses are closely related genetically to strains isolated in Nature.1978

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