潜艇艇员血清CagA-HP-IgG的调查分析

Serum Epidemiological Study of Helicobacter Pylori Infection in Submarine Personnel

目的:进行潜艇艇员中胃幽门螺杆菌(HP)感染的血清CagA-IgG流行病学调查,研究HP感染对潜艇艇员健康的影响.方法:对潜艇艇员186人和普通人群149人分别进行一般状况以及胃肠疾病诊治情况的表格调查,并测定血清产细胞毒素幽门螺杆菌抗体(CagA-HP-IgG).结果:335人中总的CagA-HP-IgG阳性率为59%,其中潜艇人员中阳性率为65%,普通人群阳性率为52%,两组比较,差异显著(P<0.05).潜艇艇员吸烟者CagA-HP-IgG阳性率为73%,不吸烟者CagA-HP-IgG阳性率为59%,两组无统计学意义.有胃肠症状者CagA-HP-lgG阳性率为76%,无症状者CagA-HP-IgG阳性率为55%,两者相差显著(P<0.01).结论:潜艇艇员中胃幽门螺杆菌感染率显著高于普通人群,且有胃肠症状者更为明显,为我们防治提供了理论依据.

Object: Serum CagA-HP-IgG epidemiological Study was carried out to evaluate the incidence of helicobacter pylori (HP) infection its effects on submarine personnel. Method; questionnaire study was performed on 186 subjects of submarine personnel and 149 subjects of general population for common physical conditions and previous gastrointestinal disorders, and serum CagA-HP-IgG was determined for all the sub-jects. Results: in all 335 subjects, 59% were found to be CagA-HP-IgG positive. The positive rate was 65% for the submarine personnel group and 52% for the general subjects, there is a statistical difference between the two groups (P<0. 05). The positive rate was 73% for the smoker subgroup of the submarine personnel and 59% for nosmoker subgroup of the submarine personnel, with no statistical difference. The positive rate was 76% for submarine personnel with gastrointestinal symptoms and 55% for submarine personnel with no gastrointestinal symptoms, there is also a statistical difference between the two groups (P<0. 01). Conclusion: The incidence of HP infection is significantly higher in submarine personnel than that of the general population, and is particular higher in submarine personnel with gastrointestinal symptoms. Our findings will provide theoretic basis in prevention and treatment of gasrointestinal diseases in submarine personnel.