新生儿坏死性小肠结肠炎62例疗效观察

Treatment of 62 Cases With NEC

目的:探讨62例新生儿坏死性小肠结肠炎(NEC)的诊治与疗效。方法:62例中早产儿及足月未成熟儿32例,足月儿30例。手术10例,其中肠切除肠吻合4例,肠造瘘6例;52例行保守治疗。本组病例均在综合治疗的基础上给予静脉高营养(TPN)疗法。TPN液经周围静脉输入。应用TPN时间为6～30d。在实验室监测情况下用TPN。结果:治愈56例,治愈率为90.3％。死亡6例,占9.7％。结论:新生儿NEC应早期诊断,在综合治疗的基础上应用TPN疗效满意。

Objective: To study the diagnosis, treatment and curative effect of 62 cases with NEC. Methods: Among the 62 cases, 32 were premature or full-term immature infants,30 cases were full-term infants. Fifty-two cases were treated with conservative treatment.Ten cases underwent operations:4 with enterectomy and entero-anastomosis, 6 with enterostomy. All cases, no matter operated on or not,received TPN via peripheral vein on the basis of complex treatment. The duration of TPN application was 6 to 30 days. Laboratory monitoring were conducted during TPN applicati on periold. Results: Fifty-six (90.3%) were cured. Six(9.7%) died. Conclusions: NEC should be early diagnosed. The curate effect of TPN therapy with complex treatment for NEC is quite astisfactory.