摘要
Easily available chiral ketones were employed for the synthesis of optically active pyridyl alcohols, which were applied in the asymmetric diethylzinc addition to aldehydes, up to 89.4% e.e. was obtained using D-fructose-derived pyridyl alcohol.
Easily available chiral ketones were employed for the synthesis of optically active pyridyl alcohols, which were applied in the asymmetric diethylzinc addition to aldehydes, up to 89.4% e.e. was obtained using D-fructose-derived pyridyl alcohol.
基金
Project (Nos. 29790127 and 29872045) supported by the National Natural Science Foundation of China.
