摘要
Objective: To analyze longitudinal binary data by using generalized linear models. The correlation between repeated measures were considered. The general method for analyzing longitudinal binary data was given. Methods: Generalized estimating equations (GEE) proposed by Zeger and Liang was used. For sevens covariance structures, one method was given for estimating regression and correlation parameters. Results: Regression and coerelation parameters were estimated simultaneously. A Set of program was finished and an example was illustrated. Conclusion: Longitudinal dsta often occur in medical researches and clinical trials. For solving the problem of correlation between repeated measures, it is necessary to use some special methods to cope with this Kind of data.
Objective: To analyze longitudinal binary data by using generalized linear models. The correlation between repeated measures were considered. The general method for analyzing longitudinal binary data was given. Methods: Generalized estimating equations (GEE) proposed by Zeger and Liang was used. For sevens covariance structures, one method was given for estimating regression and correlation parameters. Results: Regression and coerelation parameters were estimated simultaneously. A Set of program was finished and an example was illustrated. Conclusion: Longitudinal dsta often occur in medical researches and clinical trials. For solving the problem of correlation between repeated measures, it is necessary to use some special methods to cope with this Kind of data.