Et_2AlCl-Mediated Reaction of α-4(20)-Epoxy-5α-hydroxy Taxinine B

Et_2AlCl-Mediated Reaction of α-4(20)-Epoxy-5α-hydroxy Taxinine B

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摘要 An α-4(20)-epoxy-5α-hydroxytaxinine B 1, when treated with diethylaluminum chloride, underwent reactions involving intramolecular substitution along with deacetylation or addition leading to new rings. Two novel 1-deoxy compounds 2 and 3 were isolated and fully characterized. An α-4(20)-epoxy-5α-hydroxytaxinine B 1, when treated with diethylaluminum chloride, underwent reactions involving intramolecular substitution along with deacetylation or addition leading to new rings. Two novel 1-deoxy compounds 2 and 3 were isolated and fully characterized.

作者 Qian CHENG, Takayuki ORITANI, Tohru HORIGUCHI (Laboratory of Applied Bioorganic Chemistry, Graduate School of Agricultural Science Tohoku University, 1 -1 Tsutsumidori-Amamiyamachi, Aoba-ku, Sendai 981, Japan.)

出处《Chinese Chemical Letters》 SCIE CAS CSCD 2000年第3期199-202,共4页 中国化学快报（英文版）

基金 Giant-in-Aid for scientific reserch from the Ministry of Education, Science and Culture of Japan JSPS fellowship to DL Q. Che

关键词 Antitumour compounds taxoides EPOXIDE diethylaluminum chloride. Antitumour compounds, taxoides, epoxide, diethylaluminum chloride.

分类号 O621 [理学—有机化学]

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Chinese Chemical Letters

2000年第3期

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Et_2AlCl-Mediated Reaction of α-4(20)-Epoxy-5α-hydroxy Taxinine B

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