^(131)I治疗甲状腺机能亢进症260例近期疗效观察

Observation of immediate curative effect about 260 cases of hyperthyroidism treated with1311

目的 观察^(131)碘(^(131)Ⅰ)治疗甲状腺机能亢进症(甲亢)的近期临床疗效。方法 选择适合^(131)Ⅰ治疗的病例,测定甲状腺吸^(131)Ⅰ率并行甲状腺显像,估算甲状腺的重量。根据经验公式并参考病人的病情、年龄、病程,确定较为确切的治疗量,呆用一次性口服法。治疗后3个月、6个月、12个月复诊。结果 治疗260例甲亢中,225侧痊愈,治愈率86.5％,16例未完全缓解者,其中8例1年后给予第2次^(131)Ⅰ治疗。随访1年时发生甲状腺功能减低(甲低)19例,甲低发生率为7.3％。甲低者口服甲状腺素片替代治疗,维持甲状腺功能正常。结论 ^(131)Ⅰ治疗甲亢是一种安全、有效、复发率低的方法。

Objective Immediate curative effect in treatment of hyperthyridism with131 I was investigated. Methods The patients of hyperthyroidism were singled out and suitable for therapy with131 I,we determined more reliable therapeutic dose with taking orally once on the basis of thyroid iodine-131 uptake ..the weight of thyroid rou-tine dose formula and patients'age, condition .course. Those patients have come back to the hospital for a check after 3..6..12 months.Results 225 had restored health in 260 cases of hyperthyroidism with131 I, the cure rate was 86. 5% ,only 16 cases were not complete lysis,8 cases were given second after a year. We have found 19 cases of hy-pothyroidism after a year,the occurance rate was 7.3%. Thyroid hormone replacement was performed to maintain thyroid function.Conclusion It is method of safe..effective and low recurrent to treat hyperthyroidism with131I.