血脂康治疗老年原发性高脂血症临床疗效观察

Effect of XueZhiKang on primary hyperlipidemia in elderly patients

目的 验证血脂康对老年原发性高脂血症的调脂作用及安全性。方法 58例老年原发性高脂血症患者服用血脂康(600mg.二次/日)治疗。服药前及服药后4、8周测定血脂、肝肾功能等指标,其中20例8周后改半量(600mg一次/日)维持8周,再测血脂等。结果 (1)血脂康治疗4周时,TC和TG分别下降20.67％和21.66％,HDL—C上升17.71％,差异显著。继续服药至8周时,TC和TG下降达25.95％和34.40％,HDL—C上升21.88％,疗效更显著。(2)疗效显著后改半量维持治疗,血脂维持稳定,未见反弹。(3)无明显肝、肾功能损害等毒副作用。结论 血脂康可显著降低老年原发性高脂血症患者的TC和TG,升高HDL—C,对老年人安全可靠,疗效显著后减量维持疗效稳定。

Objective To validate the efficacy and safety of XueZhikang in elderly patients with primary hyperlipidemia-Methods 58 patients with primary hyperlipidemia were treated with XueZhiKang (600mg,two times a day). Serum lipid,liver and renal fucctions were measured before treatment and 4 and 8 weeks after treatment .Results Compared with basal valueTC and TG decreased by 20.67% ,25.95%,and 21.66% ,21.66% after 4 and 8 weeks of the treatment,respectively,meanwhile HDL-C raised by 17.71% and 21.88%. There were no significant;side effect on liver and renal functions observed.Conclusion XueZhiKang can decrease sig-nificantly TC and TG.and can increase HDL-C in elderly patients with primary hyperlipidemia,It is a safe and efficacious durg for elderly patients.