氟化钠药物牙膏中总氟含量测定方法的研究

The Study on Testing Method of the Total Fluorine in the Toothpaste Containing Sodium Fluoride

探讨了以EDTA/THAM溶液作为金属离子掩蔽剂和OH-离子的pH调节剂 ,用氟离子选择电极测定NaF药物牙膏中总氟含量的测定方法。进行了不同条件、不同仪器、不同方法的对比试验 ;不同物质的干扰试验 ;方法的重现性 ,精密度考查(相对标准偏差<1 %)和回收试验(回收率在99 %～101 %之间)。

This article makes an inquiry into the testing method on the total fluorine in the toothpaste containing NaF with using fluoride selective electrode and using EDTA/THAM solution as ion masking agent and pH conditioning agent of ion. Doing corresponding experiment by choosing different conditions, instruments and methods, doing interference experiment by choosing different matters, doing experiment on repetition performance of method, doing checking on precise degree(relative standard deviation<1 percent)and doing experiment on recycle(recycle rate between 99 and 101 percent).