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白细胞介素-2在结肠癌患者血清中变化的临床意义

Changes of Serum IL Levels in Colonic Cancer
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摘要 采用放射免疫法,测定45例结肠癌患者血清白细胞介素-2(IL-2)含量。结果发现:结肠癌患者血清IL-2水平明显低于正常人(P<0.01),并且随肿瘤的恶性度增高及病情的加重,血清IL-2水平明显降低,手术后血清IL-2水平回升,与手术前比较有显著性差异(P<0.01)。提示:血清IL-2水平能够反映结肠癌患者的免疫状况,也可作为疗效观察的一项参考指标。 The levels of serum IL 2 in 45 cases of colonic carcinoma were measured by radioimmunoassay.The results showed that the level of serum IL in colonic cancer is much lower than that in normal group ( P <0.01).The level of serum IL 2 is dramaticaly low in the patients with advanced cancer,but the level of serum IL 2 raised soon after operation and revealed significant difference with that of preoperation ( P <0.01). All these suggest that the levels of serum IL 2 can present the immunological status in patients of colonic cancer,may reflect the conolition of these patients and can also be used as a good parameter for observing the effects of therapy.
出处 《华夏医学》 1999年第1期19-20,共2页 Acta Medicinae Sinica
关键词 结肠癌 放射免疫 白细胞介素-2 colonic cancer radioimmunoassay IL 2
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二级参考文献2

  • 1章卫平,中华微生物学和免疫学杂志,1995年,15卷,321页
  • 2曹雪涛,白细胞介素2的基础与临床,1990年,80页

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