奥美拉唑防治脑出血合并上消化道出血临床观察

Clinical Observations on the Effect of Omeprazole in Preventing and Treating Cerebral Hemorrhage Complicatied by Hemorrhage of Upper Digestive Tract

观察奥美拉唑在预防及治疗脑出血合并上消化道出血的临床疗效，将４０例脑出血患者随机分为治疗组、对照组各２０例。对２０例脑出血患者早期使用奥美拉唑胶囊２０ｍｇ，１次／ｄ。其上消化道出血发病率为５％，病死率为０，均较对照组明显降低（Ｐ＜０．０１）。表明奥美拉唑是预防和治疗脑出血合并上消化道出血的最有效药物之一。

The aim of this study is to observe the clinical effect of omeprazole in preventing and treating cerebral hemorrhage complicated by hemorrhage of upper digestive tract.Forty cases of cerebral hemorrhage were divided into treated group and control group randomly,each 20 cases.Every patient in treated group was given omeprazole capsule 20mg once daily,the morbidity of hemorrhage of upper digestive tract was 5% and the mortality was 0,being markedly low than those of control group ( P <0.01).This indicates that omeprazole is one of the effective drugs to prevent and treat the complication (hemorrhage of upper digestive tract) of cerebral hemorrhage.