预混型人胰岛素治疗46例糖尿病患者的疗效观察

Clinical observation of Premixed Insnlin in the Treatment of Patients with Diabetes

目的 比较诺和灵预混型人胰岛素与传统自行混合猪胰岛素治疗糖尿病的效果。方法对46例有胰岛素治疗适应症患者先行混合猪胰岛素(长效+短效)治疗,待血糖稳定后,改用预混型人胰岛素诺和灵30R治疗。结果 预混型人胰岛素较混合猪胰岛素对血糖控制优良率上升56.5％,FBG及PBG均数分别下降3.7及3.4mmol.L^(-1)(P<0.01),并降低每日胰岛素总量平均约10个单位,幅度约25％(P<0.01);副作用极少,用胰岛素笔注射使给药更为方便。结论 预混型人胰岛素是具有胰岛素使用适应症糖尿病患者较为理想的选择。

Objective To compare the effects of premixed insulin ( PI) with conventional self - mixedporcine insulin (SMI). Methods 46 patients with diabetes were treated with PI(Novolin 30R insulin ) after they had been treated with SMI. Results PI decreased about 25% of the total insulin need per day (average l0u. d -1 )and got an ideal glycemic control rate(97. 8% ). Conclusion The PI represented a safe,convenient and effective alternative to conventional SMI. In addition , PI delivering by a pen - type syringe was much easier than the conventional SMI delivering.