洛赛克治疗应激性溃疡合并上消化道出血62例

The effects of Losec in treating stress ulcer With upper gastrointestinal bleeding

目的:观察洛赛克治疗应激性溃疡合并上消化道出血的疗效。方法:62例应激性溃疡合并上消化道出血患者随机分为两组:洛赛克组(40mg,iv,bid,疗程3～10天)共33例;法莫替丁组(20mg,iv,gtt,bid,疗程3～10天)共29例。结果:洛赛克组止血的显效率和总有效率分别为63.63％和93.93％;法莫替丁组止血的显效率和总有效率分别为34.48％和75.86％。洛赛克组平均止血时间为24.63±14.47小时,法莫替丁组平均止血时间为35.68±20.02小时。结论:洛赛克治疗应激性溃疡合并上消化道出血的止血效果明显优于法莫替丁。

To observe the effects of Losec in treating stress ulcer with upper gastrointestinal bleeding. 62 patients with upper gastrointestinal bleeding from stress ulcer were randomly divided into two groups. 33 patients were treated with Losec (40mg,iv, Bid) and 29 patients were treated with Famotidine (20mg,iv gtt,Bid) fira period of 3-10 days. The hemostatic rate of Losec group was 63. 63% by 1 day and 93. 93% by 3 days,whereas that of Famotidine gruop was 34. 48% by 1 day and 75. 86% by 3 days respectively. The average time of stanching of Losec group was 24. 63 hours ± 14. 47 hours, whereas that of Famotidine group was 35. 68 hours ± 20. 02 hours. Losec is more effective in halting bleeding than Famotidine in patients with upper gastrointestinal bleeding from stress ulcer.