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云南甘草总皂甙对氧自由基诱导羊心肌细胞膜Na^+,K^+-ATP酶活性降低的保护作用 被引量:1

Effects of Saponins of Glycyrrhiza Yunnanensis on the Decrease of Na+, K+-ATPase Activity Induced by Oxygen Free Radicals
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摘要 云南甘草总皂甙对正常羊心肌细胞膜Na^+,K^+-ATP酶活性无影响;但对氧自由基诱导羊心肌细胞膜Na^+,K^+-ATP酶活性的降低有明显保护作用,随浓度增高,酶的活性逐渐升高,与对照组比较,总皂甙浓度为0.2mg·L^(-1)时,酶的活性恢复27.9%,浓度为0.8mg·L^(-1),酶的活性恢复46.6%。 The study showed that saponins of gxly - cyrrhiza yunnanensis (SGY) had no significant effects on Na+, K+-ATPase activity in the normal sheep meocardial sarcolemma, but had a significant protective effect on the reduction of Na+, K+-ATPase activity induced by oxygen free radicals. With the increase of SGY concentrations, Na+, K+-ATPase activity was elevated. Compared with the control groups, the emzyme activity increased by 27.9% at 0.2mg · L-1, and 46.6% at 0.8 mg · L-1.
出处 《大连大学学报》 1998年第2期76-79,共4页 Journal of Dalian University
关键词 云南甘草总皂甙 心肌细胞膜 Na^+ K^+-ATP酶 超氧阴离子自由基 氧自由基发生系统 羟自由基 saponins of glycyrrhiza yunnanensis myocardial sarcolemma Na+, K+-ATPase superoxide anion free radical generation system hydroxyl radical
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