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Aβ相关乙醇脱氢酶的研究进展 被引量:1

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摘要 阿尔茨海默病(Alzheimer′s disease,AD)是一种以进行性智能减退为主要特征的神经系统退行性疾病,是老年期痴呆中最常见的一种,占痴呆患者的50%~60%,给家庭和社会带来沉重负担。AD发病机制有很多假说,确切机制尚不明确。最近许多学者发现Aβ相关乙醇脱氢酶(Aβbinding alcohol dehy-drogenase,ABAD)在AD的发病机制中起重要作用。本文就ABAD性质、在体内的功能及在AD发病中的作用做一综述。
作者 吴迪 张颖
出处 《中国老年学杂志》 CAS CSCD 北大核心 2011年第21期4285-4287,共3页 Chinese Journal of Gerontology
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