质子束与重离子束治疗在消化系统肿瘤中的应用现状及前景

Current status and prospectives of proton and heavier-ion beam therapy for tumor in the digestive system

Robert Wilson在1946年首先提出将质子束及重离子束应用于临床治疗。它们与常规光子放射治疗相比，具有明显的物理学优势，而且重离子还具有独特的生物学优势。随着加速器及放疗技术的发展，许多临床中心已经开始进行其对肿瘤治疗的研究。本文就质子束与重离子束治疗消化系统肿瘤的应用现状作一述评。

Particle radiotherapy using proton and heavier-ion beam was first proposed for clinical application by Robert Wilson in 1946. Compared to conventional photon radiation, proten and heavier-ion beam has significant physical advantage, and heavier-ion has unique biological characteristics. With the development of accelerator and radiation technique, it is being investigated for tumor treatment in many clinical centers. This article reviews the current status of clinical application of particle therapy using proton anti heavier-ion beam in digestive system tumor.