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肝细胞癌特异抗原的筛选 被引量:7

The Screening of Specific Antigens of Hepatocellular Carcinoma
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摘要 应用重组克隆表达抗原的血清学鉴定技术,从广西肝细胞癌中初步筛选出9个基因克隆,与肝癌患者及其他人血清的反应证明对肝癌有特异性。DNA测序结果与基因库核对,发现其中7个有同源结构;2个为无同源结构的新分子。 癝erological identification of antigens by recombinant expression cloning (SEREX)” technique was used for screening of specific antigens of hepatocelluar carcinoma. Primarily, there were nine of gene clones that had been harvestd from hepatocellular carcinoma tissues from Guangxi, a hight epidemic area in southern China. These antigens reacted to the sera of other persons showed that they were specific for the hepatocellular carcinoma. Analysis of these 9 clonic gene sequences showed that seven of them with and two without homologic structures in gene bank.
机构地区 广西医科大学
出处 《广西科学》 CAS 1998年第3期54-55,共2页 Guangxi Sciences
关键词 肝细胞癌 特异抗原 重组克隆表达抗原的血清学鉴定(SEREX) Hepatocellular carcinoma, specific antigen, serological identification of antigens by recombinant expression cloning (SEREX)
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