埋藏式电极对癫痫病灶定位价值

The value of localization of epileptogenic fuci with intracranial implanted electrode

目的：对癫痫患者行手术前脑电图描记，以观察其对致痫灶的定位价值。方法：对１７例癫痫患者采用硬膜下及深部埋藏电极检查，并且与常规头皮电极ＥＥＧ及手术中ＥＣｏＧ、ＤＥＥＧ进行比较。结果：在尖棘波的检出率上，三者阳性率比较无统计学意义（Ｐ＞０．０５）。但在致痫灶的定位率上，颅内埋藏电极ＥＥＧ准确率达８８．２％，明显高于头皮电极ＥＥＧ（Ｐ＜０．０１）；与术中ＥＣｏＧ、ＤＥＥＧ比较无明显差异（Ｐ＞０．０５），提示具有相似的定位价值。

Objectives: The value of localization of epileptogenic fuci was observed in epileptic patients preoperatively by implanted electrods in subdural and brain depth. Methods: The changes in the implanted electrodes in 17 patients with epilepty were compared with EEG recorded by scalp electrodes, and ECoG、DEEG in operation. Results: There was no significant difference among those methods in recorded spike discharge rate ( P >0.05), but in location of epileptogenic fuci,the accurate rate of preoperative ECoG was 88.2%, which was similar to that of intraoperative ECoG ( P >0.05) and much superior to that of EEG ( P <0.01). Conclusions:Those date indicate that ECoG recorded by implanted subdural and depth electrodes preoperatively is a better way for locating epileptogenic fuci.