肾活检术在小儿肾脏病诊断中的价值——附435例临床病理分析

Diagnostic value of renal biopsy in children with glomerulonephritis ——clinical pathological analysis of 435 cases

目的：为了解肾活检在小儿肾脏病诊断中的意义，对１５年来经肾活检明确诊断的４５０例肾病患儿进行了回顾性分析。方法：在Ｂ超引导下用国产肾穿刺针行１ｓ经皮肾穿刺活检术，标本分别做光镜、电镜、免疫荧光检查。结果：４５０例患儿共穿刺５５９次，满足诊断要求者４３５例，成功率达９６．７％，并统计了病理类型所占的百分比，以微小病变和轻微病变型最高，约占１２．６％。结论：①小儿肾活检术是一项较为安全而有效的检查手段；②可明确病理类型，纠正临床诊断的错误。

Objectives:To understand the significance of renal biopsy in children with glomerulonephritis,435 patients which the diognosis were established by renal biopsy in the past 15 years were analysed postspectively in details. Methods:Percutanous renal biopsy was guided by actual time scanning.The specimen was divided into three parts ,which were respectively delivered to light microscopicexamination,electro microscopic examination and immunofluorescent stainning. Results:435 cases were undergone successive renal biopsies (the mininum number of glomeruli≥10) in the total numberof 450 patients. Conclusions:The authors experience is that percutanous renal biopsy in clildren is one type of relative safe and effective diagnostic technique.It can interpret the histologic change , correct the clinical diagnostic error, and provide reliable evidence for treatment and for judging prognosis.