摘要
As a non-ionic X-ray contrast media,Ultravist had been used widely on ctinic.Serious side effects occurred during or after coronary artery angiography or PTCA in3 patients(2 male,1 female)caused by Ultravist in past three yenrs.All puticnts hadbeen tested by Meglumini Diatrizoas(Cardiografin)first,the results were nagative.Then Ultravist was used in angiography and PTCA.Reverse reaction occurred duringangiography in one patient and 30 to 60 minutes sfter engiography in two patients.These include:serious hypotension,pale,sick,vomitting,profuse sweating.bradycardia or tachycardia.The blood pressure decreased to 50/30 mmHg or couldn’tbe measured and the heart rate reached to 20-30 bpm.Emergent treatments includingintravenous injection or infusion with Atropine,Dopamine.Aramine anddexsmethasone were adapted.The blood pressure and heart rhythm returned tonormal gradually.10 to 20 days after englography,these 3 patients undergone PTCAor coronary stentlng.The same adverse reaction occurred again.During PTCA,ventricular fibrillation happened suddanly on the female patient after 5 minuteshypotension while no distinct evidences of coronary artery complication.Afteremergent treatment similar to above measures,all the three patients returned tonormal agsin in one hour to three days.Instant restenosis presented in one malepatient 3 months later,In-stent PTCA was done again and the same adverse reactionshappened again.We included that:Ultravist can cause serious side effacts,if emergentmeasures not be taken may led the patient to death;If side effects related to Ultravistoccurred during angiography,the same side effects may occur gain during or afterPTCA,and the treatment may be more difflcult;If the result of testing using loniccontrast media prlorly Is negative don’t mean that side effects related to Ultrvfst willnot happen dusing or sfter coronary nngiography and PTCA.
As a non-ionic X-ray contrast media,Ultravist had been used widely on ctinic. Serious side effects occurred during or after coronary artery angiography or PTCA in 3 patients(2 male,1 female)caused by Ultravist in past three yenrs.All puticnts had been tested by Meglumini Diatrizoas(Cardiografin)first,the results were nagative. Then Ultravist was used in angiography and PTCA.Reverse reaction occurred during angiography in one patient and 30 to 60 minutes sfter engiography in two patients. These include:serious hypotension,pale,sick,vomitting,profuse sweating. bradycardia or tachycardia.The blood pressure decreased to 50/30 mmHg or couldn't be measured and the heart rate reached to 20-30 bpm.Emergent treatments including intravenous injection or infusion with Atropine,Dopamine.Aramine and dexsmethasone were adapted.The blood pressure and heart rhythm returned to normal gradually.10 to 20 days after englography,these 3 patients undergone PTCA or coronary stentlng.The same adverse reaction occurred again.During PTCA, ventricular fibrillation happened suddanly on the female patient after 5 minutes hypotension while no distinct evidences of coronary artery complication.After emergent treatment similar to above measures,all the three patients returned to normal agsin in one hour to three days.Instant restenosis presented in one male patient 3 months later,In-stent PTCA was done again and the same adverse reactions happened again.We included that:Ultravist can cause serious side effacts,if emergent measures not be taken may led the patient to death;If side effects related to Ultravist occurred during angiography,the same side effects may occur gain during or after PTCA,and the treatment may be more difflcult;If the result of testing using lonic contrast media prlorly Is negative don't mean that side effects related to Ultrvfst will not happen dusing or sfter coronary nngiography and PTCA.
出处
《中国介入心脏病学杂志》
1998年第4期191-191,共1页
Chinese Journal of Interventional Cardiology
