摘要
为探讨肝硬化患者血清透明质酸HA与Child分级的关系,用放免法测定58例肝硬化患者血HA含量,并与Child分级主要指标进行比较。结果肝硬化患者血HA浓度明显增高,随肝功能Child分级加重而递增,A、B、C各级间HA值有显著性差异(P<0.01,P<0.05)。血HA值与白蛋白呈负相关,与总胆红素、丙氨酸转氨酶呈正相关。
In order to probe into the relationship between serum hyaluronic acid (HA) of patients with hepatocirrhosis and Child's grading,the serum HA contents of 58 patients with cirrhosis were determined by radioimmunoassay and compared with the main indexes of Child's grading. The results showed that the concentration of serum HA of patients with cirrhosis was markedly high and increased along with the exacerbation of liver function of Child's grading,the HA values between A,B,C gradings had significant difference (P<0.01,P<0.05).The serum HA value showed negative correlation with albumin and positive correlation with total bilirubin and alanine transaminase.It is considered that the concentration of serum HA may serve as the reference index in differentiating the degree of liver diseases of Child's grading and prognosis.
出处
《华夏医学》
1998年第5期10-11,共2页
Acta Medicinae Sinica