摘要
报告了三金胶囊（三金片）对尿量及尿Ｎａ＋、Ｃｌ－、Ｋ＋含量的实验研究。结果表明三金胶囊（三金片）１次口服（灌胃）后可明显增加实验动物的尿排量。在同等条件下三金胶囊１２ｇ／ｋｇ使动物７ｈ内尿量比对照组增多５０．２％，差异显著。三金胶囊可明显减少实验动物尿Ｎａ＋、Ｃｌ－的含量。而大剂量（２４ｇ／ｋｇ）三金胶囊则明显增加尿Ｋ＋的含量。三金胶囊增加尿排出量而减少尿Ｎａ＋。
A study of the effects of San Jin Capsule(San Jin Tablet) on urine and urine Na+,Cl- and K+ secretions is described.The results showed that a single oral administration of three different doses of San Jin Capsule markedly increased urine secretion in the rats.Under the same conditions,medium dose(12 g per kg body weight)of San Jin Capsule increased total volume of urine secreted by 50.2% in 7 hours after administration(P<0.05,one way ANOVA),while urine Na+and Cl- were significantly lowered in all three doses of San Jin Capsule as compared with the control(P<0.05).In large dose(24g/kg body weight),however,San Jin Capsule dramatically increased urine K+ secretion(P<0.05).It is still fuzzy to interpret the mechanisms of San Jin Capsule's effects of increasing urine secretion and lowering urinal Na+ and Cl-,but in high dose raising urinal K+.
出处
《华夏医学》
1998年第1期9-11,共3页
Acta Medicinae Sinica
