中药减少血液透析时间的临床研究

Clinical Study of Chinese Medicine (CM)on Decrease in Time of Hemodialysis

把５２例慢性肾功能不全患者分为氮质血症２０例为Ａ组：用自拟中药方治疗；尿毒症３２例以配对法分Ｂ、Ｃ两组，Ｂ组：血液透析（ＨＤ）加同Ａ组中药方治疗；Ｃ组：用ＨＤ治疗。结果：总有效率Ａ、Ｂ两组均明显优于Ｃ组（Ｐ＜０．０１），表示肾衰进展的回归系数依次为Ａ＞Ｂ＞Ｃ；血肌酐例数每月的平均下降速度依次为Ｃ＞Ｂ＞Ａ，而ＨＤ时间则为Ｃ＞Ｂ。提示：中药治疗ＣＲＩ，不但能缓解氮质血症期的病程进展，而且能延缓已进入ＨＤ治疗的尿毒症患者病程进展，从而可减少ＨＤ时间。

Fifty-two cases of chronic renal insufficiency (CRI)are reported in this paper.20 Patients of nitremia(group A)were treated mainly by CM;32patients of uraemia were divided into two (B and C)groups by pairs.Group B were treated by CM with hemodialysis (HD);group C were treated by HD only.Results showed that the total efficiency of group A and B were much better than that of group C( P <0.01).It showed that the coefficient of regression expressed the progression of CRI was successively A>B>C.It means that the drop rate of reciprocal serum creatinine (1/scr)was C>B>A in proper order.HD time was C>B.The results indicated that:the treatment of CRI with CM not only prevented progression of nitremia but also worked on ureamia with HD.Thus that decreased HD time.But the treatment of CRI using HD only could aggravate the progression of CRI.