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糖原合成酶激酶3的分型及其调控肿瘤细胞相关机制的研究进展 被引量:4

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摘要 糖原合成激酶3(glycogen synthase kinase 3,GSK3)是众多信号转导通路的中心组分,与糖尿病、精神疾病、免疫系统疾病及肿瘤等的发生发展密切相关[1],已逐渐成为信号转导通路中的研究热点。
作者 杨阳 马翠玲
出处 《解放军医学杂志》 CAS CSCD 北大核心 2011年第11期1243-1244,共2页 Medical Journal of Chinese People's Liberation Army
基金 国家自然科学基金(81071305)
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参考文献21

  • 1Jope RS, Yuskaitis CJ, Beurel E Glycogen synthase kinase-3 (GSK3): int'lanmation, diseases, and therapeutics[J]. Neurochem Res, 2007, 32(4/5): 577-595.
  • 2Ruel I., Bourouis M, Heitzler P, et al. Droso-phila shaggy kinase and rat glycogen synthase kinas-3 have conserved activities and act downstream of Notch[J]. Nature, 1993, 362(6420): 557-560.
  • 3Ruel I., Bourouis M, Heitzler P, et al. Droso-phila shaggy kinase and rat glycogen synthase kinas-3 have conserved activities and act downstream of Notch[J]. Nature, 1993, 362(6420):557-560.
  • 4Luo J. Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapy[J]. Cancer Lett, 2009, 273(2) : 194-200.
  • 5Ma C, Wang J, Gao Y, et al. The role of glycogen synthase kinast2 3β in the transformation of epidermal cells[J]. Cancer Res, 2007, 67 (16): 7756-7764.
  • 6MishraR. Glycogen synthasekinase 3 beta cancer[J]. Mol Cancer, 2010, 9, 144.
  • 7Pontano LI., Diehl JA. DNA damage dependent cyclin D1 proteoly sis: GSK3beta holds the smoking gun[J]. Cell Cycle, 2009, 8(6) 824-827.
  • 8Qu L, Huang S, Baltzl.s D, et aL Ei,doptasmic reticulum stress in duces p53 cytoplasmic localization and prevents p53-dcpcndent apopm sis by a pathway involving glycogen synthase kinase3beta[J]. Genes Dev, 2004, 18(3): 261-277.
  • 9Ali A, Hoeflich KP, Woodgett JR. C-Iycogen synthase kinase3: properties, functions, and regulation[J].Chem Rev, 2001, 101(8): 2527-2540.
  • 10白戈,唐珂,景乃禾.Wnt与其他信号通路在胚胎发育过程中的crosstalk[J].生命的化学,2002,22(4):304-308. 被引量:11

二级参考文献12

  • 1[1]Mar P et al. Science, 2000, 287:1606-1609
  • 2[2]Brennan K et al. Curr Biol, 1999, 9:707-710
  • 3[3]Axelrod JD et al. Science, 1996, 271:1826-1832
  • 4[4]Bart DS et al. J Cell Biol, 2001, 152(4):F17-F19
  • 5[5]Lee CS et al. Proc Natl Acad Sci USA, 2001, 98(20):11347-11352
  • 6[6]Hatini V et al. Genes Dev, 2000, 14(11):1364-1376
  • 7[7]Jiang J et al. Nature, 1998, 391(6666):493-496
  • 8[8]Mullor JL et al. Curr Biol, 2001, 11(10):769-773
  • 9[9]Monica A et al. Mol Cell Biol, 1999, 19(2):1427-1437
  • 10[10]Yasuhiko K et al. Cell, 2001, 104:891-900

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同被引文献46

  • 1龙洁,田卫东,郑晓辉,樊瑜波,李声伟.张力对成骨样细胞PGE_2表达的影响[J].实用口腔医学杂志,2005,21(2):160-162. 被引量:5
  • 2Jemal A, Siegel R, Xu J, et al. Cancer statistics 2010 [ J ]. CA Cancer J Clin,2010,60(5) :277.
  • 3Pan J,Zhang Q,Wang Y,et al. 26S proteasome activity is down-regulated in lung cancer stem-like cells propagated in vitro[ J]. PLoS One,2010,5(10) :e13298.
  • 4Garcia Campelo MR, Alonso Curbera G, Aparicio Gallego G,et al. Stem cell and lung cancer development: blaming the Wnt, Hh and Notch signalling pathway[ J]. Clin Transl Oncol,2011,13(2) :77.
  • 5Sananda Y,Yoshida K, Ohara M ,et al. Histopathologic eval- uation of stepwise progression of pancreatic carcinoma with immunohistochemical analysis of gastric: epithelial transcrip- tion factor SOX2:comparison of expression patterns between invasive components and cancerous or nonneoplastic intra- ductal components [ J ]. Pancreas, 2006,32 ( 2 ) : 164.
  • 6Sholl LM, Long KB, Hornick JL. SOX2 expression in pul- monary non-small cell and neuroendocrine carcinomas[ J]. Appl Immunohistochem Mol Morphol,2010,18 ( 1 ) : 55.
  • 7Ying Y, Tao Q. Epigenetic disruption of the WNT/beta- catenin signaling pathway in human cancers [ J ]. Epigenet- ics ,2009,4(5 ) :307.
  • 8Kormish JD,Sinner D,Zorn AM. Interactions between SOX factors and Wnt/beta-catenin signaling in development and disease[ J]. Dev Dyn,2010,239 ( 1 ) :56.
  • 9Mishra R. Glycogen synthase kinase 3 beta: can it be a tar- get for oral cancer[J]. Mol Cancer, 2010, 9:144.
  • 10Ghosh S, Karin M. Missing pieces in the NF-kappaB puzzle [J]. Cell, 2002, 109(Suppl):S81-$96.

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