Total Synthesis of (±)-Calanolide A and Its Anti-HIV Activity 被引量：3

Total Synthesis of (±)-Calanolide A and Its Anti-HIV Activity

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摘要 Anti-HIV agent (±)-calanolide A has been synthesized by a four-step approach startingfrom phloroglucinol, including the Pechmann reaction, Friedel-Crafts acylation, cyclization,chromenylation and Luche reduction. Anti-HIV agent (±)-calanolide A has been synthesized by a four-step approach startingfrom phloroglucinol, including the Pechmann reaction, Friedel-Crafts acylation, cyclization,chromenylation and Luche reduction.

作者 Chun Mei ZHOU Lin WANG Ming Long ZHANG Zhi Zhong ZHAO (Institute of Materia Medica, Peking Union Medical College &Chinese Academy of Medical Sciences, Beijing 100050)Xing Quan ZHANG Xiang Hong CHEN Hong Shan CHEN (Institute of Medicinal Biotechno

出处《Chinese Chemical Letters》 SCIE CAS CSCD 1998年第5期433-434,共2页 中国化学快报（英文版）

关键词 total synthesis (±)-calanolide A anti-HIV activity total synthesis, (±)-calanolide A, anti-HIV activity

分类号 O629 [理学—有机化学]

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2张传明,肖志艳,胡春,郭宗儒.HIV-1反式激活抑制剂的研究进展[J].中国药物化学杂志,2008,18(6):461-467. 被引量：2
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4Chun Mei ZHOU ,Lin WANG ,Zhi Zhong ZHAO (Institute of Materia Medica, Peking Union Medical College & Chinese Academy of Medical Sciences, Bejing, 100050).Synthesis of 11-demethyl and 6, 6,11-demethyl Calanolide A[J].Chinese Chemical Letters,1997,8(10):859-860. 被引量：2
5彭宗根,陈鸿珊,滕立.艾滋病毒1型逆转录酶抑制剂的小鼠血清活性动态研究[J].中国中西医结合杂志,2003,23(7):514-517. 被引量：3

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3郑朴荣,薛海,肖志艳,刘刚.2005～2008年抗HIV-1化学治疗新药的重要研究进展[J].药学学报,2010,45(2):154-164. 被引量：2

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1崔国友,黄初升,郑允飞,莫炳荣,陈文纳.天然产物Calanolide A的全合成研究进展[J].化工技术与开发,2006,35(11):10-16. 被引量：1
2杨光忠,陈玉.抗HIV天然产物Calanolide A及其类似物的合成进展[J].有机化学,2007,27(6):685-695. 被引量：2
3Qi GAO,Lin WANG,Xiao Tian LIANG (Institute of Materia Medica, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing 100050).Total Synthesis of (±)-Cordatolide A and its Anti-HIV Activity[J].Chinese Chemical Letters,1999,10(8):653-656. 被引量：1
4徐淑永,曾和平,魏传晚,王晓娟,谢彦.生物活性香豆素的研究进展[J].合成化学,2004,12(4):340-347. 被引量：28
5Chun Mei ZHOU ,Lin WANG ,Zhi Zhong ZHAO (Institute of Materia Medica, Peking Union Medical College & Chinese Academy of Medical Sciences, Bejing, 100050).Synthesis of 11-demethyl and 6, 6,11-demethyl Calanolide A[J].Chinese Chemical Letters,1997,8(10):859-860. 被引量：2
6LIU Shu-xia, LI Yang-guang, HAN Zeng-bo, HUANG Ru-dan and WANG En-bo (Department of Chemistry, Northeast Normal Univertsity, Changchun 130024, P. R. China) ZENG Yi and LI Ze-lin (Chinese Academy of Preventive Medicine, Beijing 100050, P. R. China).Syntheses, Characterization and Anti-HIVActivity of Charge TransferHeteropolycomplexes[J].Chemical Research in Chinese Universities,2001,17(2):127-133. 被引量：3
7李文辉,蒋启军,苏克新.抗爱滋病药物Calanolide四环香豆素的理论计算与分析[J].宝鸡文理学院学报（自然科学版）,2006,26(4):282-286.
8ZHOU Cheng-He LIU Qiang Juan F. Miravet M. Isabel Burguete Santiago V. Luis.Synthesis of Novel Histidine-based Open-chain Dipeptides, Polypeptides and Cyclopeptides with Anti-HIV Potential[J].有机化学,2003,23(z1):415-415.
9SUN Jing-bo,LIU Rong-wang,XUAN Li-li,LENG Wei-chun,WU Jin-chang.Synthesis and Anti-HIV Activity of Triazolo-fused 3 ＇,4＇-Cyclic and 4＇-Spiro Nucleoside Analogues[J].Chemical Research in Chinese Universities,2013,29(3):473-476.
10Hai Xue Tao Ma Lin Wang Gang Liu.A new method for the synthesis of N-substituted pyrroles[J].Chinese Chemical Letters,2010,21(11):1291-1294.

Chinese Chemical Letters

1998年第5期

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Total Synthesis of (±)-Calanolide A and Its Anti-HIV Activity 被引量：3

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