摘要
After being degreased with acetone, the feInal gonad of Chlamys (Azumapecten)farreri was extracted with watr, and then subjected to DEAE - cellulose column chromatogrphyy and pu-rified by Sephadex G - 100 chromatography to obain a pure female gonad glycoprotein (FGGP). The IRspectra, electrophoresis and chemical analysis of FGGP indicated tha it was a kind of acid glycoproteinand that the content of total protein and sugar were 54. 8% and 40%, respectively. Pharmacological testsshawd that FGGP could inhibit (inhibition rate of 40. 87% ) the growth of Sarorna 180 of mice.
After being degreased with acetone, the female gonad ofChlamys (Azumapecten) farreri was extracted with water, and then subjected to DEAE—cellulose column chromatography and purified by Sephadex G-100 chromatography to obtain a pure female gonad glycoprotein (FGGP). The IR spectra, electrophoresis and chemical analysis of FGGP indicated that it was a kind of acid glycoprotein and that the content of total protein and sugar were 54.8% and 40%, respectively. Pharmacological tests showed that FGGP could inhibit (inhibition rate of 40.87%) the growth of Sarcoma 180 of mice.
