甲状腺粘膜相关性淋巴瘤的诊断和治疗

Diagnosis and treatment of thyroid mucosa-associated lymphoid tissue malignant lymphoma

为探讨甲状腺粘膜相关性淋巴瘤的临床规律,治疗特点及预后,回顾性分析我院1988～1997年间收治甲状腺粘膜相关性淋巴瘤12例,男性3例,女性9例,年龄49岁～71岁平均62岁,最常见症状是无痛性快速生长肿块,甲状腺粘膜相关性淋巴瘤与淋巴细胞性甲腺炎密切相关。手术及放、化疗是有效治疗手段。

In order to study the clinical characteristics,management and prognosis of thyroid mucosa associated lymphoid tissue malignant lymphoma(T-MALT-ML). 12 cases with T-MALT-ML were studied restrospectively from 1988 to 1997. 3 males and 9 females,aged 49-71 with a median 62 years were treated by surgery in our hospital. The most common symptom was painless, rapid growing goitre (12/12), the next were dyspnoea(6/12) (hoarseness(3/12). T -MALT -ML is closely associated with Hashimoto thy-roiditis. The effective freatment for the disease is surgery with postoperative adjuvant radiotherapy and chemotherapy.