宫内节育器吲哚美辛缓释系统的制备及释放量测定

PREPARATION FOR INDOMETACIN RELEASIG-SLOWLY SYSTEM AND DETCTION OF RELEASING

采用挤出工艺制备了吲哚美辛缓释系统。并采用高效液相色谱法对其进行释放量测定。结果提示,第五天释放量相对平稳,可作为释放量检查依据。

Extruding technology was used for making the lndometacin releasing- slowly system.The releasing in vitro was determined by HPLC.The result prompted that the releasing of fifth day was relative stable so can be foundation for detecting releasing.