丙型肝炎确证实验的临床检测意义

CLINICAL APPLICATION OF CONFIRMATORY TEST FOR VIRAL HEPATITIS C

目的:评价丙型肝炎确证实验的临床使用价值。方法:对86例临床诊断的丙型肝炎患者用丙型肝炎确证实验和ELISA法测定抗-HCV,以30例非丙型肝炎患者作对照。结果:丙型肝炎确证实验和ELISA法测定抗-HCV的灵敏度(97.8％对82.4％)、特异度(100％对86.7％)、准确度(98.2％对83.1％)、误诊率(0％对13.3％)、漏诊率(2.2％对17.6％)和预示值(阳性100％对96.6％;阴性90.9％对52％)有差异,表明确证实验优于ELISA法。结论:丙型肝炎确证实验测定抗-HCV敏感度高,特异性强,可有效地减少误诊和漏诊,有很好的临床使用价值。

Objectives To investigate the clinical value of serum confirmatory test for viral hepatitis C.Methods: Tlte serum anti-HCV was detected by EIA and EL1SA in 86 patients ivith hepatitis C and 30 cases as control.Results: The sensitivity(97.8% vs 82.4 % ) ,specificity( 100% vs 86.7% ) and accuracy (98.2% vs 83.1 % ) of the EIA and ELISA tests were significantly different.Conclusion: Confirmatory test for viral hepatitis C by EIA has a good sensitivity and specificity,which can reduce mis-i diagnosis in clinical practice.