先天性肾积水患者的超微结构病理及临床分析

ELECTRONMICROSCOPY OF URETEROPELVIC JUNCTION OF CONGENITAL HYDRONEPHROSIS

对38例单纯先天性肾积水肾盂输尿管连接部（UPJ）组织作透射电镜观察，结果：其主要超微结构病理改变是平滑肌细胞间有大量胶原料堆组织堆积，平滑肌细胞相互分离，肌细胞本身发育不良，胞膜皱折、锯齿状、指状突起，线粒体肿胀破坏。提示积水的原因是UPJ部位功能性梗阻。

Electronmicroscopy of the UPJ specimens excised surgically was undertaken for 38 cases. The main histopathologic changes were an abundance of collagenous fiber tissues existing among smooth muscle cells. Vesicles and swelling were found in mitochondria with dysplasia of the muscle cells. The cause of congenital hydronephrosis was UPJ functional obstruction. Thus, the abnormal UPJ tissue should be as excised as possible in surgical treatment.