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静脉输注脂肪乳剂对成人呼吸窘迫综合征的影响 被引量：1

Effects of intravenous fat emulsions on ARDS
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摘要 脂肪乳剂中长链甘油三酯所含多价不饱和脂肪酸是多种生物活性物质（如前列腺素等）的前体，它们在成人呼吸窘迫综合征（ARDS）发病中起着极为重要的作用。长链甘油三酯用于ARDS患者可出现一过性动脉血氧分压下降和肺内分流增加，故应慎重大量使用；中链甘油三酯不含生物活性物质前体，但有较高生热作用，故宜慢速输注。理论上长链和中链甘油三酯混合输往或调整多价不饱和脂肪酸比例及使用方法，从而调控生物活性物质的产生，可对ARDS患者起一定的治疗作用。 Polyusaturated fatty acids(PUFA) in long-chain triglycchdes (LCT) serv as precur- sors to the eimids. It is eidrids that plays an irnportant role in the pathaenesis of ARDS. LCT cause temporary reduction in arterial oxygen tension and incrrase intrapulmonary shunt in patients with ARDS. So large dose of LCT should be avoided being used in patients with ARDS. Medium-chain triglyc- erides (MCT) which not containing precrsors of the eicosanoids have higher thermogic effect. Therefore they should be infused slowly. Thooretically, intravenous fat emulsions might be benificial to patients with ARDS by comining LCT with MCT or modulating the content of PUFA and infusing mehas.
作者 黄克俭 花天放
机构地区 上海市第一人民医院普外科
出处 《中华临床营养杂志》 CAS 1998年第2期81-84,共4页 Chinese Journal of Clinical Nutrition
关键词 成人呼吸窘迫综合征 脂肪乳剂 长链甘油三酯 中链甘油三酯 生物活性物质 ARDS Fat emulsion LCT MCT Eicosanoid
分类号 R563.8 [医药卫生—呼吸系统]
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参考文献12

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同被引文献10

  • 1平鹦,宋韶鸣,许植之,曹慧娟,杨伯民.外周静脉营养支持对危重早产儿营养和代谢的影响[J].新生儿科杂志,1995,10(4):161-163. 被引量：11
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中华临床营养杂志
1998年 第2期

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