摘要
The dynamics indexes, playing an important role in the cerebral circulation, will be changed significantly compared with their normal range in many cerebrovas-cular disease. The geometrical parameters of cerebrovascular may be detected by DSA or MRA scan, but the hemodynamic parameters, such as, blood flow, artery resistance and compliance must be calculated by building hemodynamics model.The cerebral circular system that has four entrances for blood flow (two carotid and two vertebral arteries) and three communicating arteries is much different from the systematic ststem which has only one entrance, ie. , the aortic. The purpose of this study is to set up a hemodynamics model with lumped parameters to describe the cerebral circulation. From this model, we get its governing equations and present a new method to calculate the hemodynamics indexes in clinical application.
The dynamics indexes, playing an important role in the cerebral circulation, will be changed significantly compared with their normal range in many cerebrovas-cular disease. The geometrical parameters of cerebrovascular may be detected by DSA or MRA scan, but the hemodynamic parameters, such as, blood flow, artery resistance and compliance must be calculated by building hemodynamics model.The cerebral circular system that has four entrances for blood flow (two carotid and two vertebral arteries) and three communicating arteries is much different from the systematic ststem which has only one entrance, ie. , the aortic. The purpose of this study is to set up a hemodynamics model with lumped parameters to describe the cerebral circulation. From this model, we get its governing equations and present a new method to calculate the hemodynamics indexes in clinical application.
作者
Ding Guang-hongDepartment of Applied Mechanics, Fudan University, Shanghai 200433, P. R. ChinaLu Chuan-zhenDepartment of Neurology, Huashan Hospital, Institute of Neurology, Shanghai MedicalUniversity, Shanghai 200040, P.R.ChinaYao Wei, Wang Yan-boDepartment of Applied Mechanics, Fudan University, Shanghai 200433, P. R. ChinaCheng Shao-HuaDepartment of Neurology, Huashan Hospital, Institute of Neurology, Shanghai MedicalUniversity, Shanghai 200040, P.R.ChinaCheng JinDepartment of Applied Mechanics, Fudan University, Shanghai 200433, P. R. ChinaGao Jian, Wang Xiao-dongBeijing 305 Hospital, Beijing 100017, P.R.China