纤维蛋白原与急性心肌梗塞

RELATIONSHIP BETWEEN FIBRINOGEN AND ACUTE MYOCARDIAL INFARCTION

本文检测了我院近7年来急性心肌梗塞(AMI)52例病人血浆纤维蛋白原(Fg),并与心绞痛组和其他疾病组对照,发现AMI和心绞痛组的Fg较其他疾病组高,AMI范围较大组较范围较小组Fg水平高,溶栓治疗后再通者26例Fg下降均超过20％,未再通者11例Fg下降<20％。提示血浆Fg水平增高是冠心病的危险因子,溶栓治疗时Fg检测可作为溶栓药物剂量和疗效的参考指标。

The level of plasmic fibrinogen (Fg) in 52 patients with acute myocardial infarction (AMD in recent seven years in our hospital was examined and compared with those of patients with angina pcctoris and other diseases. It was discovered that the plasmic Fg level in AMI group and angina ptctoris group were higher than that of the other group. Fg level of subjects with large extent AMI was higher than that of the subjects with small exent AMI. After thrombolysis therapy, Fg level decreased over 20 percent in 26 cases with coronary reflew, but less 20 percent in 11 ones of with coronary relew. It is suggested that higher plasmic Fg level was a risk factor of coronary disease and Fg could be a reference in evaluation the dosage and effect of thrombolytic drugs during thrombolysis therapy.