摘要
The purpose of this study was to evaluate the metabolic effects of parenteral nutrition(PN) via portal vein or peripheral vein. Fourteen patients undergone operations for colorectal cancer were divided into two groups randomly. Seven patients had portal venous catheter inserted during the operation. The nutrition support was started on the second postoperative day and continued for consecutive 5 days. The PN was given as a mixture which provided 6.2 gN/d and 5607 kJ/d of nonprotein energy with carbohydrate/fat energy ratio of 62%:38%. The mixture was infused via portal vein in seven cases(PV group) and via peripheral vein in the other seven cases as control (CTR group). Nitrogen balance was monitored and plasma albumin, triglyceride, cholesterol, bilirubin, alanine transaminase, and blood sugar were measured before and after PN in both groups, and no significant difference was found between the two groups. However, by the end of PN cumulative nitrogen balance in the PV group and CTR group was -0.53±2.30 gN/5d and -5.39±2.8 gN/5d (P<0.05), respectively. An increased serum potassium level was observed after fivedays PN in CTR group. The results suggest that PN via portal vein provides a beneficial effect on maintaining nitrogen balance in postoperative patients.
The purpose of this study was to evaluate the metabolic effects of parenteral nutrition(PN) via portal vein or peripheral vein. Fourteen patients undergone operations for colorectal cancer were divided into two groups randomly. Seven patients had portal venous catheter inserted during the operation. The nutrition support was started on the second postoperative day and continued for consecutive 5 days. The PN was given as a mixture which provided 6.2 gN/d and 5607 kJ/d of nonprotein energy with carbohydrate/fat energy ratio of 62%:38%. The mixture was infused via portal vein in seven cases(PV group) and via peripheral vein in the other seven cases as control (CTR group). Nitrogen balance was monitored and plasma albumin, triglyceride, cholesterol, bilirubin, alanine transaminase, and blood sugar were measured before and after PN in both groups, and no significant difference was found between the two groups. However, by the end of PN cumulative nitrogen balance in the PV group and CTR group was -0.53±2.30 gN/5d and -5.39±2.8 gN/5d (P<0.05), respectively. An increased serum potassium level was observed after fivedays PN in CTR group. The results suggest that PN via portal vein provides a beneficial effect on maintaining nitrogen balance in postoperative patients.
