深部真菌病的临床病理(附播散性真菌病尸检2例报告)

Clinical Pathology of Deep Mycosis-2 Cases With Disseminated Mycosis in Autopsy

深部真菌病无论是临床或病理均无明显特异性，极易误诊而发展为播散性真菌病死亡，多在死后尸检方得到证实。报告了２例播散性真菌病尸检所见，并进行小结，指出误诊原因，结合文献复习归纳深部真菌病的基本病变有化脓、坏死、肉芽肿形成。如有上述病变之一，应作为真菌感染的病理诊断线索，须进一步做真菌染色或多切片查找真菌体。此外还对真菌病的诱发因素、预防方法进行了总结，并指出最好发的器官为肺脏，婴幼儿的发生率远较成人高，对可疑病例尽早使用抗真菌药是提高存活率最有效的方法。

cases with disseminated mycosis in autopsy were reported and compared with the previous investigations. It could make conclusion that suppuration, necrosis and granuloma were generous histopathological appearances of deep mycosis after review of references and discussion of the causes of misdiagnosis. If one of the histopathological appearances appeared in pathology, it should further identify the fungus for diagnosis by means of staining with fungus or multiple sections. On the other hand ,remote cause and preventive treatment of mycosis were discussed in the paper and it indicated that lung was the frequently encountered organ, incidence in infant and child was much higher than that in adult and it was the effective therapy for improving survival rate that the suspect patients were treated with antimycosis as early as possible.