三氮唑核苷与脑活素治疗病毒性脑炎疗效及脑电图分析

Analysis of the Curative Effects of Combination of Ribavirin and Cerebrolysin and the Electroencephalogram on Viral Encephalitis

为评价三氮唑核苷联合脑活素治疗病毒性脑炎的疗效，把６７例病毒性脑炎病例随机分为治疗组和对照组。治疗组给予三氮唑核苷和脑活素治疗，对照组予能量合剂。结果表明治疗组发热、意识障碍和锥体束征持续时间均明显短于对照组（Ｐ＜０．０１），抽搐停止也以治疗组为早（Ｐ＜０．０５）；治疗组脑电图的恢复也明显早于对照组。两组均未发现副作用。研究结果提示。

To evaluate the curative effects of the combination regimen of ribavirin and cerebrolysin on viral encephalitis in children,67 cases of viral encephalitis were randomly divided into therapeutic group and control group.The therapeutic group was treated with both ribavirin and cerebrolysin and the control group was treated with energy drugs. The results showed that after treatment the effects in therapeutic group was superior to that in the control group in terms of improvement in clinical status,number of days needed for relief of fever,disorder of consciousness and pyramidal sign( P <0.01) as well as number of days needed for relief of convulsion ( P <0.05),the therapeutic group was also better than the control group in terms of improvement in eletroencephalogram.No side effects were observed in two groups. These results suggested that the combination of rebavirin and cerebrolysin was a safe and effective therapeutic approach to viral encephalitis in children.