SICU病人院内感染的现况调查

Nosocomial Infection in Surgical Intensive Care Unit: Epidemiology and Management

本文自1994年12月至1996年4月间连续收集手术后转入SICU监护 10 d以上,有明确院内感染证据的危重病人共14例,结果提示SICU病人院内感染的特点之一是多部位感染,具体感染部位数与手术方式及采用侵人性诊疗操作密切相关。细菌学研究发现当今主要感染致病菌 G^+球菌已上升至 35.7％,多重耐药菌株的出现和二重感染的发现预示合理而有效联合应用抗生素的重要性。

To evaluate the epidermiology of nosocomial infection in surgical intensive care unit (SICU) and its drug sensitivity of pathogenic bacteria. A retrospective study was carried out including 14 successive patients in SICU of Zhongshan hospital (admission days ≥14) from December 1994 to April 1996. The characteristics of these patients were as follows; 85. 8 % possessed multiple -site infections. The commoninfection sites were in ordes as lungs, abdominal incision, blood, digestive and urinary systems. The pathogenic organisms belonged to, Gram- positive cocci, Gram - negative bacilli and fungi, accounted for 35.7 % , 58.3 % and 6 % respectively. Gram - positive cocci were sensitive to vancomycin and rifampicin with a sensitivity rate of 84. 5 % and 69 % , whereas the Gram - negative bacilli were sensitive to amikacin and tobramycin (sensitivity rate 44.8 % , 43.1 % ) . The efiology of nosocomial infections in SICU were; malnutrition, immune-depression caused by operation, frequent use of invasive diagnos and therapentic procedures, abuse of broad - spectrum antibiotics. The management of these patients include; intensive nutritional and supportive treatment, correct use of antibiotics.