摘要
The energy absorbed by norfloxacin could be transferred to terbium(III) through chelation of norfloxacin with terbium(III), then the characteristic fluorescence emission could be observed. The interaction of serum albumins with norfloxacin have been investigated in this paper. The results showed that HSA could inhibit the energy transfer between norfloxacin and terbium(III). But, BSA could not. It was shown that the binding properties of norfloxacin to HSA and BSA were totally different.
The energy absorbed by norfloxacin could be transferred to terbium(III) through chelation of norfloxacin with terbium(III), then the characteristic fluorescence emission could be observed. The interaction of serum albumins with norfloxacin have been investigated in this paper. The results showed that HSA could inhibit the energy transfer between norfloxacin and terbium(III). But, BSA could not. It was shown that the binding properties of norfloxacin to HSA and BSA were totally different.
基金
Project supported by the National Natural Science Foundation of China.
