摘要
ＩｎｆｌａｍｍａｔｏｒｙｂｏｗｅｌｄｉｓｅａｓｅｉｎＨｕｂｅｉＰｒｏｖｉｎｃｅｏｆＣｈｉｎａＸＩＡＢｉｎｇ１，Ｓ．ＳＨＩＶＡＮＡＮＤＡ２，ＺＨＡＮＧＧｕｉＳｈｕｉ１，ＹＩＪｉＹｕｎ１，ＪＢＡＣＲＵＳＩＵＳ３ａｎｄＡＳＰＥＮ～Ａ３Ｓｕｂｊｅｃｔｈｅ...
AIM To investigate the inpatients with inflammatory bowel disease admitted to The Second Hospital, Hubei Medical University from 1986 to 1995 and analyze clinical features and follow up results of the patient in Hubei region. METHODS Data was collected retrospectively from 74 patients with inflammatory bowel disease (66 patients with ulcerative colitis and 8 patients with Crohn′s disease) hospitalized in The Second Hospital, Hubei Medical University from 1986 to 1995. RESULTS Abdominal pain, diarrhea, bloody and mucus stool and constipation are commonest symptoms of inflammatory bowel disease. Extraintestinal diseases were not common. The disease was mainly located in sigmoid and left colon in ulcerative colitis and located in ileum and colon in Crohn′s disease. Sulphasalazine and corticosteroid were effective (95%) in the treatment of ulcerative colitis, but about 42% patients had recurrence during the follow up of 1 11 years. Of 8 patients with Crohn′s disease, 5 had partial intestinal removal, and 3 treated with medicine of anti tuberculosis or metronidazole. Of 4 patients followed up for 1～8 years, 1 patient died of severe complications after surgery, 2 had recurrence with the medicine and 1 maintained remission with the treatment of sulphasalazine after operation. CONCLUSION From our data, family history of inflammatory bowel disease was seen in 5%. About 34% patients were smoking and 32% patients were alcoholic. Epidemiological investigation is urgently needed in Hubei of China to judge the strength of genetics and environmental factors in the pathogenesis of inflammatory bowel diseases.
