特发性无精子症与精索静脉曲张无精子症的生殖内分泌及睾丸病理学研究

A Comparative Study of Endocrinology and Testicular Pathology Between Idiopathic and Varicocele Caused Azoospermia

对特发性无精子症50例、精索静脉曲张无精子症16例及对照57例分别从血FSH、LH和T,睾丸体积,曲细精管直径、管壁厚度、管内上皮及间质病变情况进行了比较。二类无精子症的FSH、LH及T水平无显著差异,但特发性的FSH、精索静脉曲张的LH有较对方升高更多的趋势。二类无精子症的睾丸体积、曲细精管直径及管壁厚度无明显差异,但精索静脉曲张无精子症曲细精管内细胞脱落严重并伴有间质水肿及小血管病变,而特发性无精子症则曲细精管内生精阻滞明显。提示间质病变及有可能继发于之的曲细精管内细胞脱落是精索静脉曲线无精子症有别于特发性无精子症的重要特征。

50 cases of idiopathic azoospermia and 15 cases of varicocele caused axoospermia were compared in (he aspects of sex hormones, testicular volume, histology analysis. Serum FSH,LH and T levels showed respectively no significant difference between the two groups. No significant difference were found of testicular volume, the diameter and membrane of seminiferous tubules between the idiopathic and varicocele caused azoospermia patients. But varicocele caused azoospermia had obvious germ cell exfoliation accompanied with interstitial edema and vessel changes while the idiopathic azoospermia had distinct spermatogenic arrest. These suggest that interstitial lesion and germ cell exfoliation are the chracteristics of varicocele caused azoospermia that distinct idiopathic azoospermia.